Healio News

Previous retinal tear, detachment may increase recurrence risk

LONG BEACH, Calif.

—A previous retinal tear or retinal detachment may be a risk factor for developing a recurrent phakic retinal tear after cataract surgery, according to a speaker.“We obviously know that retinal tears are a significant concern because of the risk of retinal detachment, and the range of retinal tears after cataract surgery ranges from about 0.2% to 0.7%, especially shown in one of the recent IRIS registry studies,” Basil K. Williams Jr., MD, said at the American Society of Retina Specialists annual meeting. “Retinal detachment rates vary as well, but

15 hours 3 min ago

Healio News

Asthma mortality in Puerto Ricans differs by residence

Age-specific and -standardized asthma mortality rates were greater among Puerto Rican individuals with lower education attainment living in the U.S. vs.

in Puerto Rico, according to study data.These results were published in The Journal of Allergy and Clinical Immunology: In Practice.“The findings of this study provide a comprehensive understanding of how education influences asthma mortality rates among different racial and ethnic groups, including [Puerto Ricans],” Sylvette Nazario, MD, allergy & immunology program director at the University of Puerto Rico Medical Sciences

16 hours 29 min ago

Health – Dominican Today

Respiratory viruses surge as child deaths spike in Dominican Republic’s week 29 health report

Santo Domingo.- The Ministry of Public Health’s latest epidemiological bulletin paints a stark picture of rising respiratory infections and a worrying toll of infant fatalities during week 29 (July 13–19).

Santo Domingo.- The Ministry of Public Health’s latest epidemiological bulletin paints a stark picture of rising respiratory infections and a worrying toll of infant fatalities during week 29 (July 13–19). Authorities confirmed 22 new COVID-19 cases out of 209 samples—an 8 percent positivity rate—while 25 children under one year old lost their lives, bringing the year-to-date infant death total to 970.

The National Reference Laboratory Dr. Defilló detected active circulation of multiple respiratory viruses, including influenza B (Victoria lineage) at 8.3 percent positivity, and a combined 13.9 percent for adenovirus, parainfluenza, influenza A and respiratory syncytial virus. Sentinel surveillance recorded 24 severe acute respiratory infections, raising the 2025 cumulative to 882 cases.

Infant mortality soars amid respiratory outbreak

Child mortality remains a critical concern: neonatal deaths accounted for 85.4 percent (829) of the total infant fatalities. Public Health also reported two maternal deaths this week—one Haitian and one Dominican woman aged 20–39—bringing the maternal death count to 91, a 12 percent decline from 103 at this stage in 2024.

Vector-borne diseases held steady. Of 303 suspected malaria cases, seven tested positive, contributing to a 2025 tally of 649 laboratory-confirmed infections, with San Juan and Azua provinces most affected. Dengue fever saw 26 suspected cases and one confirmed infection, while leptospirosis recorded seven new suspicions and no additional confirmations. No deaths were linked to malaria, dengue or leptospirosis.

Regions hardest hit by COVID-19 included the National District, Espaillat and Duarte, with an incidence of 74.24 cases per 100,000 inhabitants over the last four weeks. Health officials urge continued vaccination, mask use in crowded settings and prompt medical attention for respiratory symptoms, especially among infants and pregnant women.

With respiratory pathogens on the rise and nearly a thousand young lives lost, public health experts warn that strengthened surveillance, expanded ICU capacity and community outreach are essential to avert further tragedies. The week 29 report underscores the urgent need for sustained investment in the country’s healthcare infrastructure to protect its most vulnerable citizens.

17 hours 2 min ago

Health, Local

Health | NOW Grenada

Welcome ceremony for Nigerian medical specialists

Minister for Health Philip Telesford extended thanks on behalf of the Government and People of Grenada to the Government and people of Nigeria and the Nigerian Technical Aid Corps for standing with Grenada in principle and in practice

1 day 5 hours ago

Health, PRESS RELEASE, joseph andall, nigeria, nigerian technical aid corps, philip telesford

Healio News

Topline data show upadacitinib improved severe alopecia

AbbVie released positive topline data from its phase 3 UP-AA trial demonstrating safety and efficacy for upadacitinib for severe alopecia areata in adults and adolescents.“The sudden and often unpredictable hair loss people living with [alopecia areata (AA)] experience can profoundly impact their self-esteem and mental well-being," Arash Mostaghimi, MD, MPA, MPH, associate professor of dermatol

ogy and vice chair of clinical trials and innovation, Brigham & Women's Hospital, Harvard Medical School, said in the press release. “There is a pressing need for more treatments that

1 day 13 hours ago

Health – Dominican Today

Santiago advances health tourism with new medical center

Santiago de los Caballeros.- Executives from the Specialized Hospital for Advanced Medicine (HEMA) announced that construction is nearly complete, with the grand opening scheduled for November 30, 2025. Located at kilometer 8.5 of the Duarte Highway in Puñal, Santiago, HEMA is poised to become a key player in both national healthcare and international health tourism.

Santiago de los Caballeros.- Executives from the Specialized Hospital for Advanced Medicine (HEMA) announced that construction is nearly complete, with the grand opening scheduled for November 30, 2025. Located at kilometer 8.5 of the Duarte Highway in Puñal, Santiago, HEMA is poised to become a key player in both national healthcare and international health tourism.

The hospital will feature 177 rooms, 40 permanent and 40 mobile medical offices, and specialized units for cardiology, dialysis, robotic surgery, mental health, sports medicine, and intensive care for adults, children, and newborns. The facility also includes nine operating rooms, a high-tech clinical laboratory, an imaging and pathology unit, and a modern emergency department with 26 treatment stations and 11 observation posts.

With a projected 1,140 direct and 4,000 indirect jobs in its first phase, HEMA is expected to significantly boost the regional economy.

1 day 14 hours ago

Health

STAT

STAT+: Moderna announces layoffs, and Alnylam’s heart drug sees quick uptake

Today we talk about an advance in an experimental mRNA vaccine for HIV, dive deep on Vinay Prasad’s sudden FDA departure, and more.

The need-to-know this morning

Today we talk about an advance in an experimental mRNA vaccine for HIV, dive deep on Vinay Prasad’s sudden FDA departure, and more.

The need-to-know this morning

Inside the undoing of Vinay Prasad at the FDA

Vinay Prasad’s short-lived but polarizing run as head of the FDA’s biologics division ended just 84 days in, after his aggressive push to tighten oversight on gene therapies and Covid-19 vaccines drew heat from all sides — Trump allies, RFK Jr. loyalists, Democrats, and Duchenne patient advocates.

His decision-making on Sarepta Therapeutics’ gene therapy— which he viewed as backed by staff and rooted in safety concerns — fueled political pressure that only mounted after far-right influencer Laura Loomer launched a campaign highlighting his progressive leanings and past anti-Trump comments. A powerful and extremely online regulator ran out of friends when it mattered most.

Continue to STAT+ to read the full story…

1 day 14 hours ago

Biotech, Business, Pharma, The Readout, biotechnology, drug development, drug prices, Research

STAT

STAT+: Pharmalittle: We’re reading about Prasad’s downfall at FDA, Moderna job cuts, and much more

Rise and shine, everyone, another busy day is on the way. And it is getting off to a good start here on the Pharmalot campus, where we have bright sunshine and much less humidity than in recent days. Who could ask for anything more? Actually, we could — it is time to reheat the coffee kettle for another cup of stimulation. Our choice today is … mint chocolate chip, a tasty treat.

Please feel free to join us. Remember, no prescription is required. And now, here are your tidbits. Hope you have a productive and meaningful day, and, as always, please do keep in touch. We have adjusted our settings to accept postcards and telegrams. …

Vinay Prasad had a problem. Several, actually, STAT tells us. His staff at the U.S. Food and Drug Administration kept leaking to the press. He was under attack by President Trump’s allies after moving to pull a gene therapy off the market. Democrats  were unhappy with his Covid vaccine restrictions and anti-vaccine advocates were lambasting him for approving the shots at all. He sent off an email to his team on Saturday evening, attempting to control the backlash. The agency’s recent crackdown on the gene therapy product was driven by a scientific consensus, he said. Not just him. “The motivation is solely what we think is in the public interest— the accurate judgment of benefits and risks,” Prasad wrote. By Tuesday, he was out of a job. His tenure as director of the FDA Center for Biologics Evaluation and Research lasted just 84 days. U.S. Health and Human Services Secretary Robert F. Kennedy Jr. and FDA Commissioner Marty Makary opposed dismissing Prasad, but were overruled by President Trump, according to POLITICO. Meanwhile, George Tidmarsh, the FDA’s top drug regulator, was named acting director of the FDA’s Center for Biologics Evaluation and Research, STAT notes.

Eli Lilly’s blockbuster diabetes drug Mounjaro matched the ability of an older treatment to prevent major heart complications in a large trial, results that show the medication has cardiovascular benefits on top of helping lower blood sugar and weight, STAT says. Type 2 diabetes patients taking Mounjaro experienced an 8% lower risk of cardiovascular-related death, heart attack, or stroke compared to people taking Trulicity. The data mean the drug met the study goal of showing “non-inferiority” — that is, Mounjaro did not perform worse than Trulicity, but Mounjaro was not proven to be better than Trulicity. Some doctors had hoped Mounjaro would outperform Trulicity. In a survey conducted by TD Cowen analysts, doctors assigned Moujaro a 60% chance of superiority. The demonstration of non-inferiority confirms the widely held belief that Mounjaro does benefit the heart. Doctors are likely to continue prescribing the drug at the same rate, given it is already shown to be highly effective in lowering blood sugar and reducing weight.

Continue to STAT+ to read the full story…

1 day 15 hours ago

Pharma, Pharmalot, pharmalittle, STAT+

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

AbbVie Eyes USD 1 Billion Buyout of Mental Health Drugmaker Gilgamesh

Bengaluru: Drugmaker AbbVie is in talks to acquire privately-held mental health therapeutics company Gilgamesh Pharmaceuticals in a deal worth about USD 1 billion, Bloomberg News reported on Wednesday, citing people familar with matter.

The U.S. drugmaker has spent over $20 billion on acquisitions since 2023 as its flagship rheumatoid arthritis treatment, Humira, lost patent protection.

Gilgamesh is a clinical-stage company developing therapies for psychiatric disorders, including depression, anxiety and post-traumatic stress disorder.

In May, AbbVie said it is partnering with Gilgamesh to develop therapies for psychiatric disorders, under which Gilgamesh could receive up to $1.95 billion in option fees and milestone payments.

Deliberations over the acquisition are ongoing and could be delayed or fall apart, Bloomberg News reported.

AbbVie and Gilgamesh did not immediately respond to Reuters' requests for comment.

Also Read: AbbVie seeks USFDA nod for combination regimen of Venclexta, Acalabrutinib for previously untreated patients with Chronic Lymphocytic Leukemia

1 day 23 hours ago

News,Industry,Pharma News,Latest Industry News

Health | NOW Grenada

GFNC headquarters officially on Archibald Avenue

The Grenada Food and Nutrition Council (GFNC) is headquarters is now located on Archibald Avenue in St George’s

View the full post GFNC headquarters officially on Archibald Avenue on NOW Grenada.

The Grenada Food and Nutrition Council (GFNC) is headquarters is now located on Archibald Avenue in St George’s

View the full post GFNC headquarters officially on Archibald Avenue on NOW Grenada.

2 days 11 hours ago

Health, Notice, PRESS RELEASE, archibald avenue, gfnc, grenada food and nutrition council

PAHO/WHO | Pan American Health Organization

PAHO’s Virtual Campus for Public Health surpasses 4 million users

PAHO’s Virtual Campus for Public Health surpasses 4 million users

Cristina Mitchell

30 Jul 2025

PAHO’s Virtual Campus for Public Health surpasses 4 million users

Cristina Mitchell

30 Jul 2025

2 days 15 hours ago

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

AbbVie seeks USFDA nod for combination regimen of Venclexta, Acalabrutinib for previously untreated patients with Chronic Lymphocytic Leukemia

North Chicago: AbbVie has announced the submission of a supplemental New Drug Application (sNDA) to the U.S.

North Chicago: AbbVie has announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for the fixed-duration, all-oral combination regimen of VENCLEXTA (venetoclax) and acalabrutinib in previously untreated patients with Chronic Lymphocytic Leukemia (CLL), offering CLL patients another VENCLEXTA combination regimen with the potential for time-limited treatment.

The submission is based on the positive results from the Phase 3 AMPLIFY trial. The combination regimen of VENCLEXTA and acalabrutinib improved progression-free survival (PFS) compared to standard chemoimmunotherapy in previously untreated patients with CLL.

"This FDA submission marks a milestone for CLL treatment with the potential approval for the first oral combination regimen of VENCLEXTA and acalabrutinib for previously untreated patients with chronic blood cancer. This new fixed-treatment duration approach could allow patients the opportunity for time off treatment, if approved, and be potentially practice-changing in frontline CLL care," said Svetlana Kobina, vice president, global medical affairs, oncology, AbbVie.

AMPLIFY is an AstraZeneca-sponsored, global, multi-center Phase 3 trial evaluating VENCLEXTA plus acalabrutinib alone or combined with obinutuzumab versus chemoimmunotherapy in patients with previously untreated CLL without del(17p) or TP53 mutation.

Data presented at the 2024 American Society of Hematology Annual Meeting showed that the fixed-duration combination regimen of VENCLEXTA and acalabrutinib reduced the risk of disease progression or death by 35% vs chemoimmunotherapy (HR 0.65; 95% CI: 0.49-0.87; p=0.004). The safety profile of the VENCLEXTA and acalabrutinib combination regimen is consistent with the known safety profile of each individual therapy alone.

VENCLEXTA (venetoclax) is a first-in-class medicine that selectively binds and inhibits the B-cell lymphoma-2 (BCL-2) protein. In some blood cancers, BCL-2 prevents cancer cells from undergoing their natural death or self-destruction process, called apoptosis. VENCLEXTA targets the BCL-2 protein and works to help restore the process of apoptosis.

VENCLEXTA is being developed by AbbVie and Roche. It is jointly commercialized by AbbVie and Genentech, a member of the Roche Group, in the U.S. and by AbbVie outside of the U.S. Venetoclax is approved in more than 80 countries, including the U.S.

2 days 22 hours ago

News,Industry,Pharma News,Latest Industry News

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