PAHO Director meets with Brazilian President to discuss public health priorities

Oscar Reyes

5 Jul 2023

The generic drug unit of Germany's Fresenius said on Monday the price for Idacio, its copycat version of Abbvie's top-selling rheumatoid arthritis drug, will be at a 5% discount to Humira's list price. Reuters Health Information

The KIT D816V mutation causes the clonal mast-cell illness known as indolent systemic mastocytosis. In order to compare the effectiveness and safety of avapritinib vs placebo in patients with ISM receiving the best supportive care, this research was carried out.

Avapritinib 25 mg once a day (n=141) or placebo (n=71) were given out randomly to patients with moderate to severe ISM (total symptom score [TSS] of 28; scores range from 0 to 110, with higher values indicating more severe symptoms). The 14-day average of the patient-reported severity of 11 symptoms served as the main endpoint for measuring mean change in TSS. Reduced levels of serum tryptase, blood KIT D816V variant allele fraction, TSS (50% and 30%), bone marrow mast cells (50%), and quality-of-life indicators were among the secondary end objectives.

The key findings of this study were:

Avapritinib-treated individuals saw a drop in TSS of 15.6 points (95% CI, 18.6 to 12.6) from baseline to week 24, as opposed to a fall of 9.2 points (13.1 to 5.2) in the placebo group; P = 0.003.

A 50% decrease in blood tryptase level was attained from baseline to Week 24 in 76/141 patients (54%; 45% to 62%) in the avapritinib group as opposed to 0/71 patients in the placebo group; P 0.001.

Avapritinib caused greater edema and alkaline phosphatase elevations than the placebo; nonetheless, there were few cases of therapy termination due to side effects.

Avapritinib exhibited superiority to placebo in treating symptoms in patients with mild to severe symptomatic ISM on BSC during this 24-week blinded phase of the PIONEER study. Overall AE incidence was comparable amongst the groups, and discontinuation rates were low. The current 5-year open-label extension is intended to assess the durability of avapritinib's effectiveness and safety.

Reference:

Gotlib, J., Castells, M., Elberink, H. O., Siebenhaar, F., Hartmann, K., Broesby-Olsen, S., George, T. I., Panse, J., Alvarez-Twose, I., Radia, D. H., Tashi, T., Bulai Livideanu, C., Sabato, V., Reiter, A., Pongdee, T., … Maurer, M. (2023). Avapritinib versus Placebo in Indolent Systemic Mastocytosis. In NEJM Evidence (Vol. 2, Issue 6). Massachusetts Medical Society. https://doi.org/10.1056/evidoa2200339

NOW IN its third year, the General Accident Insurance Company’s annual blood drive proceeds will facilitate donations to the Chain of Hope Foundation for local open-heart surgeries. With initial targets set at 50 units of blood, the 58 Half-Way...

Thirty-four persons of Amerindian descent as well as several activists of the women’s rights organisation, Red Thread, on Tuesday demanded broad-based health, legal and financial support for the 16-year old girl who alleged that she was raped by Local Government Minister Nigel Dharamlall. “Apolitical coordination of support for the child, with Indigenous groups and communities ...

Santo Domingo.- Contrary to the claims made by Hogar Crea Dominicana Dominicana regarding the presence of fentanyl in the country and the treatment of two individuals by the organization, the National Directorate for Drug Control (DNCD) and the National Drug Council (CND) have denied these allegations.

According to the DNCD, in their efforts to combat drug trafficking in the country, they have not seized fentanyl or “zombie drugs” during the tenure of Vice Admiral José Manuel Cabrera Ulloa.

The DNCD and the CND’s response came after César Richardson, a representative of Hogar Crea Dominicana based in Santiago de los Caballeros, confirmed the existence of the drug to Listín Diario. They also highlighted that the National Institute of Forensic Sciences (INACIF) has not confirmed the presence of fentanyl in the drugs that have been previously analyzed. Adding on,  states that they have conducted searches and interdictions in public spaces as indicated by the media reports, resulting in the arrest of individuals and confiscation of various other types of substances. The DNCD assures the public that they will continue their operations and interventions and are committed to addressing complaints of this nature and any others that may arise. The entity emphasizes that all seizures conducted by the institution are sent to INACIF under chain of custody for analysis, which certifies the type and weight of each substance.

Similarly, the CND, in a statement, confirms that fentanyl, an opioid estimated to cause the death of 200 people every day in the United States due to overdose, has not been identified in any illegal narcotics during the current administration of the anti-narcotics authorities. The CND highlights that INACIF maintains an extensive database that allows the identification of approximately 300 variants of fentanyl.

The statement specifies that the interventions conducted in the public spaces mentioned in television programs have resulted in the arrest of individuals and the confiscation of other substances, according to reports from INACIF.

Additionally, the Ministry of Public Health has reported no epidemiological alerts related to deaths caused by a possible overdose of fentanyl in the country.

The candidates who have qualified for NEET UG 2023 and have filled online registration form of GGSIPU earlier, and have paid the Non-Refundable Registration Fee of Rs. 1500, such candidates are required to enroll for a centralized online counseling participation fee of Rs 1000 (non – refundable) through Net Banking/Debit Card/Credit Card. The last date to pay is 6.7.2023 up to 11.50 pm.

The candidates who have qualified for NEET UG 2023 and have not filled online registration form of GGSIPU earlier and have not paid the Non-Refundable Registration Fee of Rs. 1500, such candidates are required to register and pay the registration fee of Rs 1500 online and subsequently required to enroll for a centralized online counseling participation fee of Rs 1000 (non – refundable) through Net Banking/Debit Card/Credit Card. The last date to pay is 6.7.2023 up to 11.50 pm.

The candidates are required to check their Enrolment status for the centralized online counseling process and confirmation of fee payment on the website (https://ipu.admissions.nic.in). They must take the printout of the online fee confirmation receipt with the transaction details to be retained for all future reference.

The payment of counseling participation fees does not guarantee admission, as the centralized online process for counseling is based on merit in the respective entrance test.

Documents verification –

Online verification of documents by the University

Closing Date MBBS, BSc Nursing

The candidate claiming benefits under the reserved category has to
upload the relevant supporting documents duly issued
by Competent Authority.

The candidates may kindly read Admission Brochure to see the details
of documents required for being eligible to claim benefits under the Reserved
Category and for the ARMY category, please upload Appendix 9(A)/9(B)/9(C) of the Admission Brochure 2023-24.

10.07.2023 (11:50 PM)

The candidates note that University's Verifying Officer
shall raise queries in cases where the document(s) is deficient, or any
discrepancy is observed. Candidates are advised to revert back/ upload the
required documents immediately to claim the benefit of the reserved
category on merit.

The online registration and submission of counseling
participation fees for admission in program MBBS and BSc (Hons) Nursing based on merit of NEET UG 2023 will be in respect of the following medical
colleges/institutes affiliated with Guru Gobind Singh Indraprastha University,
New Delhi -

MBBS -

1. North DMC Medical College & Hindu Rao Hospital — NDMC (MC), Hindu Rao Hospital, Malkaganj, New Delhi (Admissions to be made against 85% State Quota seats only in respect of candidates who have completed their 11th & 12th class from any school located in the NCT of Delhi).

2. Dr. Baba Saheb Ambedkar Medical College and Hospital, Sector 6, Rohini, Delhi (Admissions to be made against 85% State Quota seats only in respect of candidates who have completed their 11th & 12th class from any school located in the NCT of Delhi)

3. Army College of Medical Sciences, Near Base Hospital, Delhi Gantt., New Delhi (Admissions to be made against 100% sanctioned intake). The admission to the ALMS i.e. Army College of Medical Sciences, is for the children of eligible serving Army personnel, Ex-Army personnel, and war widows/widows of the Army. The children of categories of Army personnel as detailed in Chapter 7. I .4 of the Admission Brochure 2022-23 are eligible, and they are required to upload the relevant certificate Appendix 9 (A), 9(B), 9(C) & 9 (D) as given against the category applicable to them as proof of their eligibility for admission to ALMS.

All the concerned candidates/stakeholders are hereby informed that the admission of 100% seats in the MBBS program at VMMC & Safdadung Hospital, New Delhi, and ABVIMS, Dr. RML Hospital, will be conducted by the Medical Counselling Committee, DGHS. Hence, whosoever is desirous of seeking admission to these 02 affiliated medical colleges/institutes may apply on the website of MCC, DGHS. (https://mcc.nic.in).

BSC (Hons) Nursing –

1. Lakshmi Bai Batra College Of Nursing

2. St. Stephen's College Of Nursing, Tis Hazari, Delhi (Christian Minority)

3. College of Nursing Hindu Rao Hospital

4. College of Nursing Kasturba Hospital

5. Panna Dai College of Nursing, DDU

6. Shakuntala Devi College or Nursing

All the concerned applicants/stakeholders are hereby informed that the admission of 1 00% seats in the BSc (Hons) Nursing program at the College of Nursing, Safdariung Hospital, New Delhi, and College of Nursing. The Medical Counselling Committee, DGHS, will conduct Dr. RML Hospital. Hence, whosoever is desirous of seeking admission to these 02 affiliated medical colleges/institutes may apply on the website of MCC. DGHS. (https://mcc.nic.in).

Eligibility criteria

BSC (Hons) Nursing -

All candidates must appear in the National Eligibility cum Entrance Test — Undergraduate of 2023 (NEET UG 2023) and qualify to be considered for admissions.

Admission terms and conditions -

The minimum qualifying criteria for entrance test to admission to BSc Nursing is as under –

1. General 50th Percentile

2. SC/ST/OBC 40th Percentile

3. General-PwD 45th Percentile

4. SC/ST/OBC-PwD 40th percentile

5. Regarding candidates belonging to SC/ST/OBC, the marks obtained in 3 subjects, Physics, Chemistry, and Biology, shall be 40% individually.

Also Read:NEET PG, NEET MDS Counselling 2023: UP DGME issues guidelines on stipend, reservation, check out details

MBBS -

1. Candidate should be an Indian/ Overseas Indian / Nepal citizen. Non-Resident Indians and Foreign Nationals are not eligible.

2. The candidate should be medically fit to pursue the allocated course on medical examination.

3. The candidate should have attained the age of 17 years on or before 31' December of the year of his/her admission to the first year of the Course.

4. No provisional admission will be done for any result awaited or Compartment / Supplementary cases. The admission to the ACMS i.e. Army College of Medical Sciences, is for the children of eligible serving Army personnel, Ex-Army personnel, and war widows/widows of the Army. The children of categories of Army personnel, as detailed in chapter 7.1.4 of the Admission Brochure 2022-23, are eligible. They are required to upload the relevant certificate Appendix 9 (A), 9(B), 9(C) & 9 (D) as given against the category applicable to them as proof of their eligibility for admission to ACMS.

The candidate seeking admission under reserved categories has to mandatorily upload the entitled supporting certificate in his/her name. The Candidates, for further details, must read Chapter 6 (Reservation Policy) of the respective Admission Brochure 2023-24.

In case the candidate is claiming the seat reserved for DSC/DST/DOBC (wherever applicable) category, then He/ She should have passed his/ her qualifying exam from Delhi School/College and must have an SC/ST/OBC certificate issued by the Competent Authority of Govt. of NCT of Delhi only.

Reservation in OBC Category is not applicable for Master's Level and Postgraduate Diploma programs. The OBC category reservation applies only to the University School of Studies and Govt. Colleges (affiliated with GGSIPU) only.

For claiming reservation against the OBC category in Delhi Region, the candidate has to upload a valid OBC category certificate issued by a Competent Authority of Delhi in accordance with the list of OBC categories as per Govt. of NCT of Delhi. And suppose the OBC certificate is issued before 31.03.2023. In that case, it is mandatory for candidates to upload the OBC Non-Creamy Layer certificate, which should be issued after 31st March 2023 with the OBC certificate.

The EWS category reservation applies only to the University School of Studies and Govt. affiliated Colleges. This will be implemented in accordance with the Govt. of India and Govt. of NCT of Delhi orders as applicable. EWS Certificate should be issued after 31st March 2023 stating valid for year 2023-2024.

For claiming a reservation on a seat reserved for DEFENCE Category, the candidate must upload the duly filled and signed Appendix 1 of Admission Brochure 2023-24 issued by the competent authority as mentioned in Admission Brochure 2023-24 along with supporting documents. Reserved Category Candidates who fail to upload documents as per notified schedule or whose documents are not in order will forfeit his/her right to the reserved category claimed and will automatically be converted to General Category as per University rules.

For MBBS only: Candidates claiming a seat in the "Delhi Region" must have passed the qualifying examination (i.e. 11th and 12th ) from any institutes/ Colleges located in Delhi. Allotment of seats in the wrong region on account of incorrect filling of form will lead to cancellation of the allotment at any later stage, and the candidate will automatically lose the right to the seat in his bonafide region if not available at the time of cancellation of seat.

For BSc (Hons) Nursing - Candidates claiming seats in the "Delhi Region" must have passed the qualifying examination from any institutes! Colleges located in Delhi. Allotment of seats in the wrong region on account of incorrect filling of form will lead to cancellation of the allotment at any later stage. The candidate will automatically lose the right to the seat in his bonafide region if not available at the time of cancellation of the seat.

To view the notices, click on the links below –

https://medicaldialogues.in/pdf_upload/mbbs-213482.pdf

https://medicaldialogues.in/pdf_upload/mbbs-1-213483.pdf

Also Read:DCI Directs Dental Colleges To Ensure Provisional Registration Of BDS Students Before Undergoing Internship

Dr Ram Manohar Lohia Hospital, formerly known as Willingdon Hospital, was established by the British for their staff and had only 54 beds. After independence, its control was shifted to New Delhi Municipal Committee. In 1954, its control was again transferred to the Central Government of Independent India. 

RML Hospital Vacancy Details:

Total no of vacancies: 144

The Vacancies are in the department of Anesthesia, Anatomy, Biochemistry, Transfusion medicine, Community Medicine, Cardiac Anesthesia, Dermatology, Endocrinology, ENT, Gastroenterology, Medicine, Respiratory Medicine, Microbiology, Neonatology, Obstetrics & Gynaecology, Ophthalmology, Orthopedics, Pediatrics, Pathology, Psychiatry, Physiology, Pharmacology, Radiology, Surgery, Physical Medicine and Rehabilitation, and Forensic Medicine.

The date of the walk-in-interview is 6th, 7th, 8th, 10th, 11th and 12th of July 2023.

Venue for Interview:- HA-II (Academic) Section, ABVIMS Building, Academic Block, Ground Floor, Dr. RML Hospital New Delhi – 110001.

For more details about Qualifications, Age, Pay Allowance, and much more, click on the given link:

https://medicaljob.in/jobs.php?post_type=&job_tags=RML+Hospital+Jobs&location=&job_sector=all

Eligible Candidates (How to Apply)?

Interested & eligible candidates may present themselves for registration as per the scheduled date & Time in HA.2nd Section, Academic Block, Ground Floor, ABVIMS Building, ABVIMS & Dr. R.M.L. Hospital, New Delhi.

The candidates must bring the filled application form (as per Annexure) and the following original certificates at the time of registration (with one set of self-attested copies of all documents) [The documents should be serially page numbered]:

1. Class 10th Pass certificate for age proof.

2. Mark Sheet of MBBS (Part I, II, and Final Year)

3. MBBS Degree

4. MD/MS (PG) Attempt Certificate.

5. MD/MS/DNB Degree/Diploma/Provisional Pass Certificate from University.

6. Proof of publication/presenting paper in indexed PUBMED Journal only, if any.

7. Caste/Community/Disability Certificate (if applicable). OBC Certificate with required validity as mentioned above.

8. NOC from present employer (if employed).

9. Registration Certificates for eligibility as mentioned in eligibility Criteria.

All information regarding results, offer letters, joining, etc. will be uploaded on the hospital website (www.rmlh.nic.in) only. DrWalk-In RML Hospital will not make individual communication with any candidates.

The crucial date of determination of eligibility will be the date of the Interview.

Note:- Dr. R.M.L Hospital will not make individual communication with any candidate all updates regarding the interviews, results, offer letters, etc will be uploaded on the hospital website: www.rmlh.nic.in only. The applicants are advised to visit the website regularly for any updates.

Also Read:Vacancies For Assistant Professor Post At Dr Baba Saheb Ambedkar Medical College and Hospital, Delhi: Apply Now